The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis
نویسندگان
چکیده
منابع مشابه
The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis.
The IGFI receptor promotes malignant progression and has been recognized as a target for cancer therapy. Clinical trials with anti-IGFIR antibodies provided evidence of therapeutic efficacy but exposed limitations due in part to effects on, and the compensatory function of, the insulin receptor system. Here, we report on the production, characterization, and biologic activity of a novel, IGF-ta...
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ژورنال
عنوان ژورنال: Molecular Cancer Therapeutics
سال: 2015
ISSN: 1535-7163,1538-8514
DOI: 10.1158/1535-7163.mct-14-0751